The Brothers Bissell's flagship; a brightly dank ale that threads many needles. HOPS: Falconer's Flight, Centennial, Apollo, Eureka, Chinook MALTS: 2-Row, Maine 2-Row, Maine Flaked Wheat, Flaked Oats, Caramel 20. The Craft Beer Geek sez: Heady Topper may be considered the epitome of New England IPAs, but for the Beer Geek’s money, Bissell Brothers’ The Substance is right up there, if not better, and a lot easier to get a hold of. You don’t need to know a guy who knows a guy. Hitting the zesty tangerine notes of classic NE IPAs with a well balanced piney bite, The Substance is a serious contender.